The star has donated the full amount of his £25,000 Mercury Prize cash to the trust for venues, which operates to save the United Kingdom's grassroots live music spots.
Fender was given the prize on mid-October as his new release People Watching was chosen as the top album of the past year.
Fender has decided to give the cash to the trust, in recognition of the crucial part local spots played in his beginning days.
"I would not have achieved what I am doing today if it wasn't for all the performances I performed around the North East, and elsewhere, when I was starting out," stated Sam Fender. "These spaces are legendary, but they are facing challenges."
Beginning in 2023, more than 150 of these locations have shut down – approximately one-sixth of the total UK scene.
Over the past year, well-known musicians including Pulp, Coldplay, the singer Katy Perry and Ed Sheeran have all aided the Music Venues Trust in its attempts to support the industry, by adding a minor surcharge to their ticket prices, which goes to help smaller concert halls.
Fender also took part, raising over £100k on his recent tour to support 38 grassroots venues across the UK.
The donation helped venues that were facing potential shutdown due to challenges caused by floods, fires and family tragedies, as well as regulatory hurdles, court cases and neighbor objections.
Some locations obtained funding support in improving amenities and technical equipment that helped performers and audiences.
"The idea that money from concerts in big venues supports the independent spots, where it all starts for performers like me, is just logical," the star has stated.
Fender is among several artists to give his award winnings to worthy causes.
In they received the prize in the year 1996 for their release their work, lead singer Cocker stated that the band would give their cash to the non-profit the charity.
That year, musician Ms Dynamite split her bounty between a few organizations, like the children's charity and a Sickle Cell organization.
"And I donated a grand to Highgate Newtown, to their gymnastics class, because I did gymnastics when I was growing up and they needed updated gear," she shared with the media.
Two years ago, the band gave their winnings to the youth organization that developed their band, alongside other independent music bodies.
Also 1994 winners they gave their winnings to a charity for MS after a friend was found to have the condition.
"Receiving the award was ample," remarked artist the singer. "The prize was the bonus but we could do without the cherry, because we had the honor. So our victory impacted the lives of others."
Last week, the trust shared it had saved several small stages in south-east England, by bringing them into community ownership.
The Joiners in that area and The Croft in the city were acquired under the Own Our Venues program, which is supported by the arts council and supporters who acquire "stakes" in the properties.